Creating a better tomorrow for 1,150,000 cancer patients

Cancer has touched so many lives—and yet current treatments have limited effectiveness. At Sygnomics, we believe that personalization is the key to improving the odds for millions of cancer patients around the world. And this can only be achieved through advanced technology like the AI-driven SPOT-AI platform. It’s a huge leap forward for oncology, one that can extend lives and offer hope to cancer patients and their families.

Our Journey

The SYGNAL (Systems Genetic Network Analysis) technology underlying the SPOT-AI platform was developed by our cofounder Dr. Nitin Baliga at the Institute for Systems Biology (ISB).

Utilizing that technology, Baliga and serial entrepreneur Ashutosh Tiwary founded Sygnomics in 2020, after Tiwary spent two years as an Entrepreneur in Residence at ISB.

Using gifts from the Washington Research Foundation, along with a $2M technology commercialization grant from the Washington State Andy Hill Care Fund in 2023, Sygnomics performed preliminary clinical validations, which showed that SPOT-AI can provide an end-to-end service that addresses an unmet need helping oncologists build personalized therapies for each patient.

In October 2023, Sygnomics was chosen to participate in the Computational Health stream of the Creative Destruction Labs (CDL) incubator. We’ve benefited tremendously from the advice and guidance of mentors with deep domain expertise in oncology, genomic testing, clinical trials, drug commercialization, and regulatory and payer approval processes. These mentors have helped us define and build our product offerings, our commercialization strategy, and our business plan—all of which have been vetted four times with the broad CDL team of mentors and investors.

The Team

Sygnomics is led by a team of experienced scientists, oncologists, engineers and entrepreneurs. Meet the minds developing this revolutionary technology.

Ashutosh Tiwary

Cofounder and CEO

Serial Tech entrepreneur with 2 exits, transitioned to genomics and biology.  Entrepreneur in residence at ISB. Built tech businesses at Teradata, AWS, Microsoft, and Mercury Interactive

Dr. Nitin S. Baliga

Cofounder and Interim Chief Science Officer

Invented SYGNAL technology at ISB with > $15M in grants and research publications cited over 50,000 times. Professor and Director at Institute for Systems Biology

Dirk van den Boom

Dirk van den Boom

Board Member

Innovative CEO in the Life Sciences/ Diagnostics industry with a strong track record of developing and commercializing leading technologies in liquid biopsy and genetic testing

 

 

Dr. Thomas Brown

Chief Medical Officer

Internationally renowned oncologist,  and cancer researcher. CMO at Syapse, Exec Dir of the Swedish Cancer Institute (SCI), COO at Univ Of Arizona Ca Ctr, Sr leadership roles at MD Anderson for a decade, clinical research at Duke & UTHSC-San Antonio

 

 

Dr. Anoop Patel

Clinical Lead for Glioblastoma

Neurosurgical Oncologist focused on brain tumors with clinical and translational practice. Leader at Duke Brain Tumor Center, trained at University of Washington, Massachusetts General Hospital, Harvard

Serdar Turkarslan

 

Serdar Turkarslan

Science & Computational Biology Lead

Senior Research Scientist with extensive experience in using systems approaches to build global scale, predictive network models to uncover mechanistic underpinnings of cancer

Atif Kureishy

 

Atif Kureishy

Business Advisor

Interim Head of AI & Business Development

He brings deep experience at the intersection of enterprise software, applied AI, and commercialization, with a track record of building and scaling data-driven platforms in regulated industries

John Milne

 

 

Dr. John Milne

Clinical Advisor

Interim Head of Clinical Operations

Senior Physician Executive with an MBA focused on the intersection of clinical innovation, operational excellence, business strategy and patient experience.  SVP of strategy at Providence Health System, CMO at Swedish Medical Center, Founder Oldivai Capital

Our Advisors

Sygnomics is supported by an esteemed advisory board of pioneering medical and biotech leaders. Meet the visionaries helping us validate, refine, and accelerate the impact of our technology.

Neal Mody

Strategic Business Advisor

Investor & Builder of Transformative Companies | Leading Innovation in Life Sciences, Deep Tech, and Biomanufacturing

Dr. Jesse Salk

Dr. Jesse Salk

Oncology Advisor

Physician scientist, genomic biomarker expert. Practicing oncologist at VA Puget Sound, Associate Professor UW, Fred Hutch. Founder TwinStrand Biosciences Inc, Director at multiple diagnostic and therapeutic life sciences companies

Abhishek (Abhi) Agrawal

Pharma Advisor

Commercial expert, with senior leadership roles at GSK, NOVARTIS, IQVIA and resident advisor to Gates Venture & ADDF.

Felix Frueh

Regulatory Advisor

Biochemist and entrepreneur; biomarker and regulatory expert; Executive Partner at Opus Three Partners LLC, a life sciences advisory group specialized in personalized medicine; Director at multiple public and private diagnostics and pharmaceutical companies.

Help shape the future of personalized oncology

Join us in our mission to offer cancer patients and their families real hope. Your investment could impact millions of patients. Let’s chat about the future.